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Abstract: Analgesia for paediatric tonsillectomy and adenoidectomy with intramuscular clonidine.


Freeman KO, Connelly NR, Schwartz D, Jacobs BR, Schreibstein JM, Gibson C.


Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA.


Paediatr Anaesth. 2002 Sep;12(7):617-20.


BACKGROUND: After undergoing tonsillectomy and adenoidectomy (T&A), children may experience significant pain. Clonidine, an alpha2 agonist, exhibits significant analgesic properties. The current investigation sought to determine whether intramuscular (I.M.) clonidine would decrease pain in paediatric patients undergoing T&A. METHODS: Thirty-nine children undergoing elective T&A were studied. Following inhalational anaesthetic induction, fentanyl (2 microg x kg(-1)) was given intravenously, acetaminophen (paracetamol) (30 was given rectally and the children then randomly received an i.m. injection of either normal saline or clonidine (2 microg x kg(-1)). Perioperative analgesic requirements in the postanaesthesia care unit and at home following hospital discharge were evaluated. RESULTS: There were no significant demographic, analgesic consumption, haemodynamic or pain score differences between the groups. CONCLUSIONS: We do not recommend adding i.m. clonidine (2 microg x kg(-1)) to the analgesic regimen of children undergoing tonsillectomy and adenoidectomy.


ENT Surgery Anaesthesia Analgesia Paediatric Pain